excede antibiotic for horses
A maximum of 20 mL per injection site may be administered.
In the PK study, one horse treated with 6.0 mg/lb (2X) EXCEDE experienced a mild episode of colic the day after the second injection of EXCEDE.
The horse recovered without treatment.Injection sites were observed in both studies.
The originating document has been archived. If acute diarrhea is observed, additional doses of EXCEDE should not be administered and appropriate therapy should be initiated.Due to the extended exposure in horses, based on the drug’s pharmacokinetic properties, adverse reactions may require prolonged care. Like other cephalosporins, ceftiofur is bactericidal, Each mL of this ready-to-use sterile suspension contains ceftiofur crystalline free acid equivalent to 200 mg ceftiofur, in a caprylic/capric triglyceride and cottonseed oil based suspension.7-[[2-(2-Amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]- 3-[[(2-furanylcarbonyl)thio] methyl]-8-oxo-5-thia-1- azabicyclo[4.2.0]oct-2-ene 2-carboxylic acidEXCEDE Sterile Suspension is indicated for the treatment of lower respiratory tract infections in horses caused by susceptible strains of Administer two intramuscular injections to horses, 4 days apart, at a dose of 3.0 mg/lb (6.6 mg/kg). The study housing (multi-horse pens on concrete slabs) and diet (free choice alfalfa/grass mix and once a day pellets) may have contributed to the development of foot pain.
A causal relationship between ceftiofur and foot pain could not be definitively determined.Store at controlled room temperature 20° to 25°C (68° to 77°F). All rights reserved. Animal Healthcare Professionals. If allergic reaction occurs (e.g. Animals experiencing adverse reactions may need to be monitored for this duration of time.The use of ceftiofur has not been evaluated in horses less than 4 months of age and in breeding, pregnant, or lactating horses. Do not use in horses intended for human consumption. Remove contaminated clothing. Ceftiofur is not active against The minimum inhibitory concentration (MIC) values for ceftiofur against label-claim pathogens isolated from lower respiratory tract infections in horses enrolled in a 2007-2008 field effectiveness study are presented in Table 4.
Therapeutic drug concentrations are maintained for 6 days after the second injection (or a total of 10 days from the beginning of treatment) against EXCEDE Sterile Suspension is contraindicated in horses with known allergy to ceftiofur or to β-lactam (penicillins and cephalosporins) group antimicrobials. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert.We comply with the HONcode standard for trustworthy health information - All MICs were determined in accordance with the A double masked, randomized, negative control, field study evaluated the effectiveness of two intramuscular doses of 6.6 mg/kg EXCEDE Sterile Suspension administered 4 days apart for the treatment of lower respiratory infections caused by Two studies, a target animal safety (TAS) study and a pharmacokinetic (PK) study (see In the TAS study, healthy adult horses received 6 intramuscular (lateral neck) injections of EXCEDE Sterile Suspension at doses of either 3.0 (1X), 6.0 (2X) or 9.0 (3X) mg/lb with a 4 day interval between each injection. QUEST PLUS contains an additional active ingredient for efficacy against tapewormsConnect directly to valuable dairy management resources and expertsThe most "veterinarian recommended" and "producer used" prostaglandin in the marketDelivers the peace of mind and profitability that come with no milk discardEffective and convenient treatment for acute metritis in cattleOne injection treats and controls swine respiratory disease for 7 daysProtect sows and gilts from costly breeding herd diseases — parvovirus, leptospirosis and erysipelasPrevention and control of necrotic enteritis, increased rate of weight gain and improved feed efficiency in poultrymodified-live vaccine that helps poultry companies reduce their overall Salmonella loadDelivers reliable predictions of genetic merit based on test results of core traitsRepresents the latest advancement in Angus genotyping technology.Earn continuing education credits and stay current on industry developments with Zoetis’ convenient, on-demand learning solutions.Veterinary Students, Veterinary Technicians and Recent GraduatesAnimal health expertise and results-focused resources for high-performing teams and leaders.
This makes treating equine respiratory infections less stressful for the horse and more convenient … The injection site reactions in EXCEDE-treated horses resolved over 1 to 20 days.At least one episode of diarrhea, loose, soft, or cowpie stools were observed in 25 of 278 (9%) of the EXCEDE-treated horses and 7 of 95 (7%) of the placebo-treated horses.
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